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Infectious Disease Testing at the Delaware Public Health Laboratory


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Sexually Transmitted Infections (STI) Testing

Syphilis serology:

  • RPR screening test, qualitative and quantitative
  • TPPA confirmatory test
  • VDRL, qualitative and quantitative (cerebral spinal fluids only)

Chlamydia, Gonorrhea and Trichomonas:

  • Nucleic acid amplification testing (NAAT)
  • Gonorrhea culture

Human Immunodeficiency Virus (HIV):

  • 4th Generation Antigen/Antibody Immunoassay detection
  • HIV 1 and 2 differentiation Immunoassay confirmation

Hepatitis C Virus (HCV):

  • HCV Antibody Immunoassay Detection
  • HCV Viral Load – quantitative

Molecular Assays by Real Time polymerase Chain Reaction (PCR)

  • Bordetella pertussis, parapertussis, or holmseii Multiplex Assay
  • Carbapenemase Resistant Organism Testing – multiple assays for resistance mechanisms
  • Chikungunya, Dengue, Zika Virus Multiplex Assay (requires consultation with Office of Infectious Disease Epidemiology – OIDE)
  • Coxiella burnetii (requires consultation with OIDE)
  • Eastern Equine Encephalitis (EEE) and West Nile Virus (WNV) (animal organs and/or mosquitoes)
  • Ebola virus (requires consultation with OIDE)
  • Foodborne outbreaks for: Salmonella, Shigella, Shigatoxin-producing E. coli, Listeria
  • Influenza A and B typing, Influenza A subtyping (H1N1 pandemic, H3N2); Influenza B genotyping (B/Yamagata, B/Victoria). Detection of avian strains (H5N1 and H7N9) (requires consultation with OIDE)
  • CDC Respiratory Virus Panel with respiratory targets listed here
  • Herpes Simplex 1 and 2 viruses, Varicella Zoster Virus Multiplex Assays
  • Measles and Mumps viruses
  • Mycobacterium tuberculosis and Mycobacterium avium complex Multiplex Assay
  • Norovirus type GI and GII Multiplex Assay
  • Novel Coronavirus (requires consultation with OIDE)
  • Potential agents of bioterrorism (See our Laboratory Preparedness page)
  • SARS-CoV-2

Bacteriology (identification and susceptibility)

  • Stool Culture
  • Urine Culture
  • Strep Culture
  • Wound or Miscellaneous Culture
  • Carbapenemase Detection – modified Carbapenemase Inactivation Method (mCIM)
  • Confirmation of Culture Independent Diagnostic Testing (CIDT)
  • Confirmation of Enteric Pathogens – Salmonella species. Shigella species, Shiga-toxin-producing E. coli (STEC), Listeria monocytogenes, Vibrio species
  • Antibiotic Susceptibility Testing

Clinical Outbreak Surveillance:

  • Campylobacter species
  • Listeria monocytogenes
  • Salmonella
  • Shigella
  • Vibrio spp.
  • Shiga-toxin producing E. coli (STEC)


  • Specimen digestion and concentration
  • AFB smear (Auramine O or Kinyoun) and culture
  • Mycobacterium tuberculosis complex (MTB) Antimicrobial susceptibility testing
  • PCR for MTB complex and Mycobacterium avium complex (MAC)
  • Quantiferon

Food Microbiology (Epidemiologic/Outbreak Investigation only):

  • Bioterrorism Agents – culture and Real Time PCR
  • Bacillus cereus – culture
  • Listeria species – Culture and WGS
  • Salmonella species – Culture, PCR and WGS
  • Shigatoxin–producing Escherichia coli – Culture, PCR, serotyping and WGS
  • Shigella species – Culture, PCR and WGS
  • Staphylococcus aureus – Culture
  • Vibrio species – Culture Confirmation and WGS
  • Campylobacter – Culture Confirmation and WGS


  • West Nile Virus (WNV); Saint Louis Encephalitis (SLE); IgM Microsphere immunoassay (human serum and spinal fluid)
  • WNV and Eastern Equine Encephalitis (EEE) — IgM Enzyme immunoassay performed on chicken blood, for detection of WNV and EEE in chickens placed around areas of high mosquito prevalence (in summer months). Also known as "sentinel chicken" program.
  • Rabies detection by Direct Flurescent Antibody (DFA) from brain stem and cerebellum (requires OIDE consultation)


Tests Performed by the State Clinic Labs:

  • Urine Dip Stick
  • Pregnancy – Urine
  • HIV Rapid
  • KOH Prep
  • Hemocue
  • Blood Lead

Visit our Laboratory Preparedness page for testing forms and procedures related to agents of biological and chemical terrorism.

Return to the Delaware Public Health Laboratory home page.

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