Frequently Asked Questions HUMAN PAPILLOMA VIRUS (HPV/GENITAL WARTS) What is the HUMAN Human Papilloma Virus, more commonly known as HPV, is a PAPILLOMA VIRUS (HPV)? viral infection spread through skin-to-skin sexual contact. HPV is a group of over 100 different strains or types. Over 30 of these are sexually transmitted, and they can infect the genital area, like the skin of the penis, vulva, labia, or anus, or the tissues covering the vagina and cervix. Genital warts are single or multiple growths or bumps that appear in the genital area, and sometimes form a cauliflower-like shape. How do people get The types of HPV that infect the genital area are spread genital HPV infections? primarily through genital contact. Most HPV infections have no signs or symptoms. Therefore, most infected persons are unaware they are infected, yet they can transmit the virus to a sex partner. What are the signs and Some but not all people with genital HPV infection get visible symptoms of genital genital warts. Most people who have a genital HPV infection infection? are symptom-less and do not know they are infected. What are genital warts? Some but not all people with genital HPV infection get visible genital warts. Genital warts appear as single or soft, moist, pink or red swellings that appear in the genital area. They can be raised or flat, single or multiple, small or large. Some cluster, forming a cauliflower-like shape. Warts can appear on the vulva, in or around the vagina or anus, on the cervix, and on the penis, scrotum, groin or thigh. Warts can appear within several weeks after sexual contact with an infected person, or they can take months to appear. Who is at risk for genital Anyone who has sex is at risk for genital HPV infection. HPV infection? How is genital HPV Most women are diagnosed with HPV on the basis of infection diagnosed? abnormal Pap smears. Pap smears are the primary screening tool for cervical cancer or pre-cancerous conditions, many of which are cell changes related to HPV. How is genital HPV There is no "cure" for HPV infection, although in most infection treated? women the infection goes away on its own. The treatments provided are directed to the changes in the skin or mucous membrane caused by HPV infection, such as warts and pre-cancerous changes in the cervix. What is the connection Approximately 10 of the 30 identified genital HPV types can between HPV infection lead, in rare cases, to development of cervical cancer. A Pap and cervical cancer? test can detect pre-cancerous and cancerous cells on the cervix. Regular Pap testing and careful medical follow-up, with treatment if necessary, can help ensure that pre-cancerous changes in the cervix caused by HPV infection do not develop into life-threatening cervical cancer. How can genital HPV The surest way to avoid transmission of sexually transmitted infection be prevented? diseases is to abstain from sexual contact, or to be in a long- term mutually monogamous relationship with a partner who was tested and is known to be uninfected. Latex or polyurethane male condoms, when used consistently and correctly, can reduce the risk of transmission of HPV, but cannot eliminate HPV transmission. On June 8, 2006, the Food and Drug Administration (FDA) licensed the first vaccine developed to prevent cervical cancer and other diseases in females caused by certain types of genital human papilloma virus (HPV). The HPV vaccine is recommended for 11-12 year-old girls but can be administered to girls as young as 9 years of age. The vaccine also is recommended for 13-26 year-old females who have not yet received or completed the vaccine series. For more information: Call the Centers for Disease Control and Prevention at 1-800-232-4636, TTY: 1-888-232-6348 In English and Spanish. Contact Number: STD Program, (302) 744-1050 Revised: 03/2007 Doc. # 35-05-20/07/03/11